A camelid antibody candidate for development of a therapeutic agent against Hemiscorpius lepturus envenomation
نویسندگان
چکیده
منابع مشابه
Serum TNF-α levels reflect the clinical severity of envenomation following a Hemiscorpius lepturus sting.
Hemiscorpius lepturus (H. lepturus), found in south-western areas of Iran and south of Iraq, is considered to be the most dangerous scorpion in the region, and poses a significant risk to the health of the indigenous population due to the unique, clinical manifestations associated with its sting.. In the present study, 36 patients from the Khuzestan province in the southwest of Iran, displaying...
متن کاملHemiscorpius lepturus envenomation: Manifestations and management with specific antivenom
Scorpionism is a known significant problem of medical and social importance in many tropical and subtropical regions including the Middle East. In Iran, highest prevalence of scorpion sting about 60% of all the stings has been reported from Khuzestan province. Among the 21,000 cases of reported scorpion stung patients, 12% were caused by H. lepturus, but contributed to 95% of all moralities in ...
متن کاملA review of epidemiological, clinical and in vitro physiological studies of envenomation by the scorpion Hemiscorpius lepturus (Hemiscorpiidae) in Iran.
Many of the published accounts of envenomation by Hemiscorpius lepturus (H. lepturus) are in a form that makes it difficult for non Farsi readers to access. The purpose of this review is to summarise the Iranian literature on the toxinological effects of the venom of H. lepturus using both in vivo and in vitro data and where appropriate, details of methods and ethics statements will be reported.
متن کاملAntivenom injection time related effects of Hemiscorpius lepturus scorpion envenomation in rabbits
Hemiscorpius lepturus is the most dangerous scorpion species, endemic in Khuzestan province and other southwestern areas of Iran, causing morbidity and mortality in children and adults. The efficacy of the antivenom for reversal of manifestation caused by venom of this scorpion is a controversial issue. In the present work, H. lepturus venom (1500 µg/kg) was subcutaneously injected into two ...
متن کاملhemiscorpius lepturus envenomation: manifestations and management with specific antivenom
scorpionism is a known significant problem of medical and social importance in many tropical and subtropical regions including the middle east. in iran, highest prevalence of scorpion sting about 60% of all the stings has been reported from khuzestan province. among the 21,000 cases of reported scorpion stung patients, 12% were caused by h. lepturus, but contributed to 95% of all moralities in ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2014
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fj.13-247478